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Dimosthenis (Denis) Sarigiannis
Dimosthenis (Denis) Sarigiannis Director and President of the Board of the National Hellenic Research Foundation (NHRF) and Professor of Environmental Engineering at Aristotle University Dimosthenis (Denis) Sarigiannis is Director and President of the Board of the National Hellenic Research Foundation (NHRF) and Professor of Environmental Engineering at Aristotle University of Thessaloniki, with parallel appointments at the University School for Advanced Studies of Pavia (IUSS), Johns Hopkins University Medical School and Yale School of Public Health. He holds a PhD in Nuclear Engineering from UC Berkeley. Internationally recognized as a pioneer of translational exposomics, his work quantitatively links external exposures to internal dose, molecular perturbation, and health risk across the life course. His methodological innovations integrate human biomonitoring with PBPK/PBK modelling, new approach methodologies (NAMs), and multi-omics analytics, enabling mechanistically grounded, individual-level risk models. He is equally recognized for operationalizing Safe and Sustainable by Design (SSbD) in chemicals, materials and products through AI-enabled computational toolboxes that bridge next-generation risk assessment with industrial innovation and regulatory practice. Prior to his academic career, he held senior leadership roles at the European Commission's Joint Research Centre (JRC), including Scientific Coordinator at the Institute for Health and Consumer Protection, Assistant to the JRC Director General and positions central to the development of the REACH Regulation on chemical safety. He has contributed to over 50 international research projects — coordinating 15 — and currently leads the Center of Excellence on Cancer Theranostics at NHRF and the ENVESOME Horizon Europe initiative while serving on the Management Board in the ~€400M PARC partnership. He has authored 233 peer-reviewed papers, 500 conference papers, and 28 book chapters, and has been listed among Stanford's top 2% of scientists worldwide since 2018. His contributions to the safety of pharmaceuticals and chemicals have been recognized with the Bo Holmstedt Award from Eurotox and multiple excellence prizes. Prize by the European Society of Toxicology and the Bo Holmstedt Foundation.

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