For centuries, humans have dreamed of escaping the confines of gravity through flight. Greek mythology brought us the visions of Daedalus, Pegasus, Hermes and Nike. Artist and engineer, Leonardo da Vinci, translated that vision into drawings and Codex’s. But it was the 1903 flight of the Wright Brothers who finally allowed “heavier than air” flight with an engine powered airplane. Scarcely, 58 years later, both the Soviet Union and the United States launched their first astronauts into low earth orbit (LEO) and 8 years after that, two men walked on the Moon. Ten more astronauts would walk on the Moon by 1972. The focus then changed to LEO orbiting space stations and transportation vehicles. Salyut, Skylab, and the International Space Station remained in orbit for years. The reusable Space Shuttle flew 135 flights over 30 years, retiring in 2011. Thousands of experiments in human, biological and physical sciences advanced technology in support of future human space exploration. In 2018, the US again set its sights on both the Moon and Mars. On April 1, 2026, the Artemis II mission with 4 astronauts in the Orion space capsule orbited the Moon once again. The pathway forward in this century has been set. Dr. Dunbar will share her perspective on human space exploration through her own five space shuttle flights and involvement in NASA strategic planning and put forth the vision of a future in which many nations will participate in human space exploration through the Artemis Accords..